静息态脑功能成像评价夜磨牙者的大脑默认网络(6)

OBJECTIVE:To analyze the changes of brain’s default mode network (DMN) in patients with sleep bruxism and to investigate the DMN status of patients with sleep bruxism.

METHODS:From November 2018 to May 2019, 20 patients with sleep bruxism (sleep bruxism group) diagnosed by polysomnography and 20 age-, gender-, and education-matched asymptomatic adults (control group) were recruited in the study. Brain resting-state functional MRI data were collected on a 3.0T scanner during 20:00 to 23:00. The MRI data were analyzed using independent component analysis method to extract the component of DMN. The one-sample t-test was used to make a network component template, and then the two-sample t-test used to compare the DMN components between the two groups.

RESULTS AND CONCLUSION:Compared with asymptomatic controls, patients with sleep bruxism showed a significantly weaker functional connectivity of the precuneus within the DMN (t=-3.319,P＜ 0.05), indicating that patients with sleep bruxism show abnormal functional connectivity within the DMN at brainresting state.

文章来源：《口腔疾病防治》 网址: http://www.kqjbfz.cn/qikandaodu/2021/0727/503.html